Author

Razavi-Shearer D

December 11, 2021
Progress towards achieving viral hepatitis B and C elimination in the Asia and Pacific region: Results from modelling and global reporting
Summary In 2016, Asia and Pacific countries endorsed action plans for reaching viral hepatitis elimination targets set in the Global Health Sector Strategy (GHSS) for Viral Hepatitis 2016-2021. We examine the region’s progress by modelling disease burden and constructing the cascade of care. Between 2015 and 2020, chronic HBV prevalence declined from 4.69% to 4.30%, […]

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July 13, 2021
Lives saved with vaccination for 10 pathogens across 112 countries in a pre-COVID-19 world
Summary Background Vaccination is one of the most effective public health interventions. We investigate the impact of vaccination activities for Haemophilus influenzae type b, hepatitis B, human papillomavirus, Japanese encephalitis, measles, Neisseria meningitidis serogroup A, rotavirus, rubella, Streptococcus pneumoniae, and yellow fever over the years 2000-2030 across 112 countries. Methods Twenty-one mathematical models estimated disease burden using standardised demographic and […]

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May 29, 2021
Hepatitis C elimination in Sweden: Progress, challenges and opportunities for growth in the time of COVID‐19
Summary Background & Aims In 2014, the burden of hepatitis C virus (HCV) in Sweden was evaluated, to establish a baseline and inform public health interventions. Considering the changing landscape of HCV treatment, prevention, and care, and in light of the COVID-19 pandemic, this analysis seeks to evaluate Sweden’s progress towards the World Health Organization […]

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January 30, 2021
Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study
Summary Background The past two decades have seen expansion of childhood vaccination programmes in low-income and middle-income countries (LMICs). We quantify the health impact of these programmes by estimating the deaths and disability-adjusted life-years (DALYs) averted by vaccination against ten pathogens in 98 LMICs between 2000 and 2030. Methods 16 independent research groups provided model-based […]

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September 26, 2020
A tool to measure the economic impact of Hepatitis B elimination: A case study in Saudi Arabia
Summary Background No virologic cure exists for hepatitis B virus (HBV) infection, and existing therapies are designed to control viral replication. We aimed to estimate the national prevalence of HBsAg in 2017 and study the impact of an enhanced diagnosis rate and universal treatment administration on HBV-related outcomes in Saudi Arabia. Materials and methods A […]

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August 10, 2020
Modelling hepatitis B virus infection and impact of timely birth dose vaccine: A comparison of two simulation models
Summary Hepatitis B is a global epidemic that requires carefully orchestrated vaccination initiatives in geographical regions of medium to high endemicity to reach the World Health Organization’s elimination targets by 2030. This study compares two widely-used deterministic hepatitis B models—the Imperial HBV model and the CDA Foundation’s PRoGReSs—based on their predicted outcomes in four countries. […]

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August 7, 2020
Impact of COVID-19 on global HCV elimination efforts
Summary Background & Aims Coronavirus disease 2019 (COVID-19) has placed a significant strain on national healthcare systems at a critical moment in the context of hepatitis elimination. Mathematical models can be used to evaluate the possible impact of programmatic delays on hepatitis disease burden. The objective of this analysis was to evaluate the incremental change […]

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January 16, 2020
Global prevalence of hepatitis C virus in children in 2018: a modelling study
Summary Background Hepatitis C virus (HCV) prevalence estimates for adults and high-risk groups have been widely published, but the disease burden in children is poorly understood. Direct-acting antiviral drugs, which are considered to be highly effective curative therapies for HCV, are now approved for paediatric patients as young as 3 years. Reliable prevalence estimates for […]

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October 30, 2017
Strategies to manage hepatitis C virus infection disease burden—Volume 4
Summary The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 17 countries in Africa, Asia, Europe, Latin America and the Middle East, and interventions for achieving the Global Health Sector Strategy on viral hepatitis targets-“WHO Targets” (65% reduction in HCV-related deaths, 90% reduction in new infections and 90% of infections diagnosed by 2030) […]

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October 30, 2017
The present and future disease burden of hepatitis C virus infections with today’s treatment paradigm: Volume 4
Summary Factors influencing the morbidity and mortality associated with viremic hepatitis C virus (HCV) infection change over time and place, making it difficult to compare reported estimates. Models were developed for 17 countries (Bahrain, Bulgaria, Cameroon, Colombia, Croatia, Dominican Republic, Ethiopia, Ghana, Hong Kong, Jordan, Kazakhstan, Malaysia, Morocco, Nigeria, Qatar and Taiwan) to quantify and […]

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Author

Razavi-Shearer D

Progress towards achieving viral hepatitis B and C elimination in the Asia and Pacific region: Results from modelling and global reporting

Lives saved with vaccination for 10 pathogens across 112 countries in a pre-COVID-19 world

Hepatitis C elimination in Sweden: Progress, challenges and opportunities for growth in the time of COVID‐19

Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study

A tool to measure the economic impact of Hepatitis B elimination: A case study in Saudi Arabia

Modelling hepatitis B virus infection and impact of timely birth dose vaccine: A comparison of two simulation models

Impact of COVID-19 on global HCV elimination efforts

Global prevalence of hepatitis C virus in children in 2018: a modelling study

Strategies to manage hepatitis C virus infection disease burden—Volume 4

The present and future disease burden of hepatitis C virus infections with today’s treatment paradigm: Volume 4

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Useful Links, Polaris

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