Summary Hepatitis B and C cause most cases of hepatitis in the United States and the world. The two diseases account for about a million deaths a year and 78 percent of world’s hepatocellular carcinoma and more than half of all fatal cirrhosis. In 2013 viral hepatitis, of which hepatitis B virus (HBV) and hepatitis […]
Summary Collaborators European Union HCV Collaborators: Homie Razavi, Sarah Robbins, Stefan Zeuzem, Francesco Negro, Maria Buti, Ann-Sofi Duberg, Françoise Roudot-Thoraval, Antonio Craxi, Michael Manns, Rui T Marinho, Bela Hunyady, Massimo Colombo, Soo Aleman, Krasimir Antonov, Perttu Arkkila, Kostas Athanasakis, Sarah Blach, Martin Blachier, Antonio J Blasco, Filipe Calinas, Jose L Calleja, Peer B Christensen, Matthew E Cramp, Esther Croes, Robert J de Knegt, Victor de Ledinghen, Jean-Michel Delile, Chris Estes, Karolin Falconer, Martti Färkkilä, Robert Flisiak, Sona Frankova, Ivane Gamkrelidze, Javier García-Samaniego, Jordan Genov, Jan Gerstoft, Liana Gheorghe, Adrian Goldis, Ilias Gountas, Sergeja Gregorčič, Michael Gschwantler, Jessie […]
Summary Hepatitis C virus (HCV) is a hepatotropic RNA virus that causes progressive liver damage, which might result in liver cirrhosis and hepatocellular carcinoma. Globally, between 64 and 103 million people are chronically infected. Major risk factors for this blood-borne virus infection are unsafe injection drug use and unsterile medical procedures (iatrogenic infections) in countries […]
Summary No abstract available. Countries: Spain Read the Full Report
Summary Background and aim Interferon-free direct-acting antiviral regimens for hepatitis C virus (HCV) infection have been recently available in Australia, beginning a new era in clinical and public health management of HCV infection. This study provided updated estimates of the HCV infection care cascade and burden in Australia as a reliable platform for assessing the […]
Summary This past May 2016, the World Health Organization (WHO) Member States endorsed the first “Global Health Sector Strategy on Viral Hepatitis 2016-2021” at the 69th World Health Assembly. This strategy will contribute to the achievement of the Health Goals set out in the 2030 Agenda for Sustainable Development. Member States in the Americas have […]
Summary Collaborators Polaris Observatory HCV Collaborators: Sarah Blach, Stefan Zeuzem, Michael Manns, Ibrahim Altraif, Ann-Sofi Duberg, David H Muljono, Imam Waked, Seyed M Alavian, Mei-Hsuan Lee, Francesco Negro, Faisal Abaalkhail, Ahmed Abdou, Maheeba Abdulla, Antoine Abou Rached, Inka Aho, Ulus Akarca, Imad Al Ghazzawi, Saad Al Kaabi, Faryal Al Lawati, Khalid Al Namaani, Youssif Al Serkal, Said A Al-Busafi, Layla Al-Dabal, Soo Aleman, Abdullah S Alghamdi, Abdulrahman A Aljumah, Hamad E Al-Romaihi, Monique I Andersson, Vic Arendt, Perttu Arkkila, Abdullah M Assiri, Oidov Baatarkhuu, Abate Bane, Ziv Ben-Ari, Colm Bergin, Fernando […]
Summary Background Bayesian evolutionary analysis (coalescent analysis) based on genetic sequences has been used to describe the origins and spread of rapidly mutating RNA viruses, such as influenza, Ebola, human immunodeficiency virus (HIV), and hepatitis C virus(HCV). Methods Full-length subtype 1a and 3a sequences from early HCV infections from the International Collaborative of Incident HIV […]
Summary Hepatitis C viral infection after injection drug use is very prevalent. The most important genotype causing HCV infection in PWID globally is genotype 1, as is the case in the general population, but also genotype 3 is highly prevalent in PWID. Genotype 4 is most prevalent in Africa, spreading into Europe, whereas genotype 2 […]
Summary We utilized a disease progression model to predict the number of viraemic infections, cirrhotic cases, and liver-related deaths in the state of Rhode Island (RI) under four treatment scenarios: (1) current HCV treatment paradigm (about 215 patients treated annually, Medicaid reimbursement criteria fibrosis stage ⩾F3); (2) immediate scale-up of treatment (to 430 annually) and […]
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