Summary In 2014, an analysis was conducted to evaluate the hepatitis C virus (HCV) epidemiology and disease burden in Germany. Since then, there have been considerable developments in HCV management such as the implementation of direct acting antivirals. The aim of this analysis was to assess the recent data available for Germany, establish an updated […]
Summary Background Since the release of the first global hepatitis elimination targets in 2016, and until the COVID-19 pandemic started in early 2020, many countries and territories were making progress toward hepatitis C virus (HCV) elimination. This study aims to evaluate HCV burden in 2020, and forecast HCV burden by 2030 given current trends. Methods This analysis […]
Summary Background & aims Elimination of HCV by 2030, as defined by the World Health Organization (WHO), is attainable with the availability of highly efficacious therapies. This study reports progress made in the timing of HCV elimination in 45 high-income countries between 2017 and 2019. Methods Disease progression models of HCV infection for each country […]
Summary Background & Aims Coronavirus disease 2019 (COVID-19) has placed a significant strain on national healthcare systems at a critical moment in the context of hepatitis elimination. Mathematical models can be used to evaluate the possible impact of programmatic delays on hepatitis disease burden. The objective of this analysis was to evaluate the incremental change […]
Summary Background & Aims Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are increasingly a cause of cirrhosis and hepatocellular carcinoma globally. This burden is expected to increase as epidemics of obesity, diabetes and metabolic syndrome continue to grow. The goal of this analysis was to use a Markov model to forecast NAFLD disease […]
Summary Collaborators New Paradigm of HCV Therapy Meeting Participants: Nezam H Afdhal, Rachel Baden, Cynthia Beam, Julie Krop, Clifford Brass, David Brumley, Laurent Castera, Daniel Church, Alfred DeMaria Jr, Kevin Cranston, Lynda Dee, Arnold Doyle, Julia Engstrom-Melnyk, Michael Fried, Camilla Graham, Michael Wong, William Guyer, John G McHutchison, Joe Steele, William Symonds, Ira M Jacobson, Alain Litwin, Anthony Martinez, Andrew Talal, Henry Masur, Douglas Mayers, Ronald C Renaud Jr, Shruti H Mehta, Andrew Muir, Christopher J Myatt, Stanley J Naides, Rick Pesano, William O’Brien, Christos J Petropoulos, Gastón R Picchio, Thierry […]
Summary Background Hepatitis C virus (HCV) infection is associated with chronic progressive liver disease. Its global epidemiology is still not well ascertained and its impact will be confronted with a higher burden in the next decade. Aim The goal of this study was to develop a tool that can be used to predict the future […]
Summary Background and Aim Decisions on public health issues are dependent on reliable epidemiological data. A comprehensive review of the literature was used to gather country-specific data on risk factors, prevalence, number of diagnosed individuals and genotype distribution of the hepatitis C virus (HCV) infection in selected European countries, Canada and Israel. Methodology Data references […]
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