{"id":9157,"date":"2025-07-01T05:57:00","date_gmt":"2025-07-01T05:57:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=9157"},"modified":"2026-05-29T06:08:03","modified_gmt":"2026-05-29T06:08:03","slug":"a-call-to-reclassify-the-delta-hepatitis-virus-as-an-orphan-disease","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/a-call-to-reclassify-the-delta-hepatitis-virus-as-an-orphan-disease\/","title":{"rendered":"\u547c\u5401\u5c06\u4e01\u578b\u809d\u708e\u75c5\u6bd2\u91cd\u65b0\u5f52\u7c7b\u4e3a\u7f55\u89c1\u75c5"},"content":{"rendered":"<p>\u6162\u6027\u4e01\u578b\u809d\u708e\u75c5\u6bd2\uff08HDV\uff09\u611f\u67d3\u88ab\u8ba4\u4e3a\u662f\u75c5\u6bd2\u6027\u809d\u708e\u4e2d\u6700\u5177\u4fb5\u88ad\u6027\u548c\u6700\u4e25\u91cd\u7684\u7c7b\u578b\uff0c\u4e0e\u809d\u786c\u5316\u548c\u809d\u764c\u98ce\u9669\u589e\u52a0\u76f8\u5173\u3002\u7531\u4e8e\u5176\u9ad8\u53d1\u75c5\u7387\u548c\u9ad8\u6b7b\u4ea1\u7387\uff0c\u8feb\u5207\u9700\u8981\u9488\u5bf9\u8be5\u75be\u75c5\u7684\u66f4\u591a\u7597\u6cd5\u3002\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5b64\u513f\u836f\u4ea7\u54c1\u5f00\u53d1\u529e\u516c\u5ba4\u5e94\u7ee7\u7eed\u5c06\u6162\u6027HDV\u8ba4\u5b9a\u4e3a\u7f55\u89c1\u75c5\uff0c\u5e76\u7eb3\u5165\u5f53\u524d\u548c\u672a\u6765\u836f\u7269\u6cbb\u7597\u7533\u8bf7\u7684\u8303\u7574\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0clonafarnib\u548cmyrcludex\u6b64\u524d\u5df2\u83b7\u5f97FDA\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002\u300a\u5b64\u513f\u836f\u6cd5\u6848\u300b\u5c06\u7f55\u89c1\u75c5\u6216\u75c5\u75c7\u5b9a\u4e49\u4e3a\u5728\u7f8e\u56fd\u5f71\u54cd\u4eba\u6570\u5c11\u4e8e20\u4e07\u7684\u75be\u75c5\u6216\u75c5\u75c7\u3002\u6b63\u5982\u672c\u6587\u6240\u8ff0\uff0c\u7edd\u5927\u591a\u6570\u73b0\u6709\u548c\u5386\u53f2\u6570\u636e\u5747\u652f\u6301\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002.<\/p>\n\n\n\n<p>\u5c3d\u7ba1HDV\u53ef\u5bfc\u81f4\u4e25\u91cd\u7684\u809d\u810f\u75be\u75c5\uff0c\u4f46\u5728\u7814\u7a76\u3001\u68c0\u6d4b\u3001\u6d41\u884c\u75c5\u5b66\u548c\u516c\u5171\u536b\u751f\u653f\u7b56\u65b9\u9762\uff0c\u5b83\u4ecd\u7136\u5f88\u5927\u7a0b\u5ea6\u4e0a\u88ab\u5ffd\u89c6\u3002\u7531\u4e8e\u300a\u5b64\u513f\u836f\u6cd5\u6848\u300b\u6fc0\u52b1\u5236\u836f\u516c\u53f8\u7814\u53d1\u548c\u63a8\u5e7f\u7f55\u89c1\u75c5\u6cbb\u7597\u836f\u7269\uff0c\u5c06HDV\u8ba4\u5b9a\u4e3a\u5b64\u513f\u836f\u5c06\u6709\u52a9\u4e8e\u5f00\u53d1\u9488\u5bf9\u8be5\u75c5\u6bd2\u7684\u7597\u6cd5\uff0c\u5e76\u6539\u5584HDV\u60a3\u8005\u7684\u6cbb\u7597\u6548\u679c\u3002.<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/cdafound.org\/wp-content\/uploads\/2026\/05\/Gish-2025-A-call-to-reclassify-HDV-as-an-orphan-disease.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Chronic infection with HDV is considered the most aggressive and severe form of viral hepatitis, associated with an increased risk of cirrhosis and liver cancer. Due to high morbidity and mortality, there is a clear need for additional therapies for this disease. The Food and Drug Administration (FDA)\u2019s Office of Orphan Products Development should continue [&hellip;]<\/p>\n","protected":false},"author":939,"featured_media":3104,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[2729,58,2728,28],"publication-author":[2718,2720,2721,2725,2717,2723,2719,2727,2722,2726,2724],"class_list":["post-9157","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-editorial","tag-hdv","tag-orphan-disease","tag-policy-analysis","publication-author-cohen-chari1","publication-author-gish-robert-g","publication-author-glenn-jeffrey-s","publication-author-holden-larry-r","publication-author-raymond-daniel","publication-author-razavi-homie","publication-author-stiehl-lorraine","publication-author-terrault-norah","publication-author-thomas-david-l","publication-author-wedemeyer-heiner","publication-author-wong-robert-j"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/9157","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/939"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=9157"}],"version-history":[{"count":1,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/9157\/revisions"}],"predecessor-version":[{"id":9159,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/9157\/revisions\/9159"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3104"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=9157"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=9157"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=9157"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=9157"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}