{"id":2668,"date":"2014-12-17T21:52:00","date_gmt":"2014-12-17T21:52:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2668"},"modified":"2025-01-16T15:41:52","modified_gmt":"2025-01-16T15:41:52","slug":"the-future-disease-burden-of-hepatitis-c-virus-infection-in-sweden-and-the-impact-of-different-treatment-strategies","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/the-future-disease-burden-of-hepatitis-c-virus-infection-in-sweden-and-the-impact-of-different-treatment-strategies\/","title":{"rendered":"\u745e\u5178\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u611f\u67d3\u7684\u672a\u6765\u75be\u75c5\u8d1f\u62c5\u53ca\u4e0d\u540c\u6cbb\u7597\u7b56\u7565\u7684\u5f71\u54cd"},"content":{"rendered":"<h2 class=\"wp-block-heading\">\u6982\u62ec<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u5ba2\u89c2\u7684<\/h3>\n\n\n\n<p>\u6700\u8fd1\uff0c\u745e\u5178\u63a8\u51fa\u4e86\u9488\u5bf9\u4e19\u578b\u809d\u708e\u75c5\u6bd2 (HCV) \u7684\u65b0\u578b\u9ad8\u6548\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269 (DAA)\u3002\u8fd9\u4e9b\u836f\u7269\u80fd\u5426\u7f13\u89e3\u745e\u5178\u9884\u671f\u589e\u52a0\u7684\u809d\u75c5\u8d1f\u62c5\u5c1a\u4e0d\u6e05\u695a\uff0c\u90e8\u5206\u539f\u56e0\u662f\u9ad8\u6602\u7684\u6210\u672c\u53ef\u80fd\u4f1a\u9650\u5236\u5176\u4f7f\u7528\u3002\u672c\u7814\u7a76\u7684\u76ee\u7684\u662f\u6a21\u62df\u745e\u5178\u7684\u4e19\u578b\u809d\u708e (HCV) \u75ab\u60c5\u3001\u75be\u75c5\u8d1f\u62c5\u4ee5\u53ca\u4e0d\u540c\u6cbb\u7597\u7b56\u7565\u7684\u6f5c\u5728\u5f71\u54cd\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u6750\u6599\u548c\u65b9\u6cd5<\/h3>\n\n\n\n<p>HCV \u75be\u75c5\u8fdb\u5c55\u6a21\u578b\u9884\u6d4b\u5230 2030 \u5e74\u3002\u4f7f\u7528\u65b0\u7684 DAA \u6a21\u62df\u60c5\u666f\uff0c\u5176\u4e2d\u7ef4\u6301\u5e74\u6cbb\u7597\u7387\uff08n = 1130\uff09\u3001\u964d\u4f4e\u6cbb\u7597\u7387\uff08n = 380\uff09\u4ee5\u7ef4\u6301\u9884\u7b97\uff0c\u4ee5\u53ca\u63d0\u9ad8\u6cbb\u7597\u7387\uff08n = 1430 \u6216 2260\uff09\u4ee5\u51cf\u5c11 HCV \u611f\u67d3\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7ed3\u679c<\/h3>\n\n\n\n<p>\u91c7\u7528\u76ee\u524d\u7684\u4e09\u8054\u7597\u6cd5\uff0c\u9884\u8ba1\u4e25\u91cd\u809d\u810f\u5e76\u53d1\u75c7\u548c\u6b7b\u4ea1\u4eba\u6570\u5c06\u57282021\u5e74\u8fbe\u5230\u5cf0\u503c\u3002\u5728F0-F4\u60a3\u8005\u4e2d\u4f7f\u7528\u65b0\u578bDAA\uff0c\u4fdd\u6301\u5e74\u6cbb\u7597\u7387\u4e0d\u53d8\uff0c\u52302030\u5e74\u53ef\u5c06HCV\u611f\u67d3\u4eba\u6570\u51cf\u5c1110%\uff1b\u7136\u800c\uff0c\u809d\u7ec6\u80de\u764c(HCC)\u548c\u6b7b\u4ea1\u7387\u5c06\u4fdd\u6301\u4e0d\u53d8\u3002\u5982\u679c\u5c06\u6bcf\u5e74\u6cbb\u7597\u4eba\u6570\u51cf\u5c11\u5230380\u4eba\uff0c\u5e76\u4e13\u6ce8\u4e8e\u665a\u671f\u7ea4\u7ef4\u5316(F3-F4)\u60a3\u8005\uff0c\u4e25\u91cd\u5e76\u53d1\u75c7\u5c06\u4fdd\u6301\u4e0d\u53d8\uff0c\u4f46HCV\u611f\u67d3\u603b\u6570\u5c06\u4f1a\u589e\u52a0\u3002\u5982\u679c\u5c06DAA\u6cbb\u7597\u4eba\u6570\u589e\u52a0\u4e00\u500d\uff0c\u52302030\u5e74\uff0cHCC\u53d1\u75c5\u7387\u548c\u809d\u810f\u76f8\u5173\u6b7b\u4ea1\u4eba\u6570\u5c06\u51cf\u5c1165-70%\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7ed3\u8bba<\/h3>\n\n\n\n<p>\u9650\u5236F2-F4\u60a3\u8005\u4f7f\u7528\u65b0\u578bDAA\u5e76\u6301\u7eed\u6cbb\u7597\uff0c\u6216\u589e\u52a0F0-F4\u60a3\u8005\u7684\u7528\u836f\u91cf\uff0c\u5747\u53ef\u964d\u4f4e\u6b7b\u4ea1\u7387\u548cHCC\u53d1\u75c5\u7387\u3002\u4e3a\u964d\u4f4e\u6210\u672c\u800c\u9650\u5236\u6cbb\u7597\u53ef\u80fd\u4f1a\u964d\u4f4e\u5176\u79ef\u6781\u4f5c\u7528\uff0c\u5e76\u589e\u52a0HCV\u611f\u67d3\u8d1f\u62c5\u3002\u8fd9\u4e9b\u7ed3\u679c\u53ef\u80fd\u5bf9\u672a\u6765\u7684HCV\u7ba1\u7406\u7b56\u7565\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/p>\n\n\n\n<p><strong>\u56fd\u5bb6\uff1a<\/strong> \u745e\u5178<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25515032\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Objective Recently, new highly effective direct-acting antivirals (DAAs) against hepatitis C virus (HCV) were introduced. Whether these will alleviate the anticipated increase of liver disease burden in Sweden is unknown, partly because high costs may restrict the use. The objectives were to model the HCV epidemic in Sweden, the burden of disease, and the [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3356,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[10,12],"publication-author":[586,488,583,2178,584,494],"class_list":["post-2668","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-hcv","tag-modelling","publication-author-aleman-s","publication-author-blach-s","publication-author-duberg-as","publication-author-falconer-k","publication-author-kaberg-m","publication-author-razavi-h"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=2668"}],"version-history":[{"count":6,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2668\/revisions"}],"predecessor-version":[{"id":7618,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2668\/revisions\/7618"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3356"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=2668"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=2668"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=2668"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=2668"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}