{"id":2658,"date":"2014-05-05T21:14:00","date_gmt":"2014-05-05T21:14:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2658"},"modified":"2025-01-16T15:58:16","modified_gmt":"2025-01-16T15:58:16","slug":"hepatitis-c-disease-burden-and-strategies-to-manage-the-burden-guest-editors-mark-thursz-gregory-dore-and-john-ward","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/hepatitis-c-disease-burden-and-strategies-to-manage-the-burden-guest-editors-mark-thursz-gregory-dore-and-john-ward\/","title":{"rendered":"\u4e19\u578b\u809d\u708e\u75be\u75c5\u8d1f\u62c5\u53ca\u7ba1\u7406\u7b56\u7565\uff08\u7279\u9080\u7f16\u8f91 Mark Thursz\u3001Gregory Dore \u548c John Ward\uff09"},"content":{"rendered":"<h2 class=\"wp-block-heading\">\u6982\u62ec<\/h2>\n\n\n\n<p>\u6162\u6027\u4e19\u578b\u809d\u708e\u75c5\u6bd2 (HCV) \u611f\u67d3\u4f1a\u5bfc\u81f4\u809d\u7ea4\u7ef4\u5316\u3001\u809d\u786c\u5316\u548c\u809d\u7ec6\u80de\u764c (HCC)\u3002\u8fd1\u671f\u7684\u5168\u7403\u75be\u75c5\u8d1f\u62c5\u9879\u76ee\u4f30\u8ba1\uff0c2010 \u5e74\uff0c\u5728 1.7 \u4ebf\u6162\u6027\u4e19\u578b\u809d\u708e\u60a3\u8005\u4e2d\uff0c\u7ea6\u6709 48.31 \u4e07\u4eba\u6b7b\u4e8e\u4e19\u578b\u809d\u708e\u76f8\u5173\u7684\u809d\u8870\u7aed\u6216\u809d\u7ec6\u80de\u764c\u3002\u8fc7\u53bb\u4e8c\u5341\u5e74\uff0c\u4e19\u578b\u809d\u708e\u7684\u6cbb\u7597\u624b\u6bb5\u4e0d\u65ad\u6539\u8fdb\uff0c\u6700\u65b0\u7684\u7597\u6cd5\u7b80\u5355\u6613\u884c\u3001\u7597\u7a0b\u77ed\uff0c\u7597\u6548\u663e\u8457\u3002\u5236\u5b9a\u5e94\u5bf9\u65b0\u53d1\u6d41\u884c\u75c5\u7684\u516c\u5171\u536b\u751f\u6218\u7565\u9700\u8981\u53ef\u9760\u7684\u6d41\u884c\u75c5\u5b66\u6570\u636e\u3002\u672c\u7814\u7a76\u6db5\u76d6\u6d41\u884c\u75c5\u5b66\u6570\u636e\u6536\u96c6\u3001\u8be6\u7ec6\u7684\u4e13\u5bb6\u610f\u89c1\u5f81\u96c6\u3001\u9488\u5bf9 16 \u4e2a\u56fd\u5bb6\u7684\u4e19\u578b\u809d\u708e\u75ab\u60c5\u7684\u56fd\u522b\u6570\u5b66\u5efa\u6a21\u4ee5\u53ca\u6539\u8fdb\u7684\u4e19\u578b\u809d\u708e\u6cbb\u7597\u7b56\u7565\u7684\u6f5c\u5728\u5f71\u54cd\u3002\u5206\u6790\u8868\u660e\uff0c\u4e0d\u540c\u56fd\u5bb6\u4e19\u578b\u809d\u708e\u75ab\u60c5\u5728\u611f\u67d3\u4eba\u7fa4\u7684\u5e74\u9f84\u5206\u5e03\u65b9\u9762\u5b58\u5728\u663e\u8457\u5dee\u5f02\u3002\u6b64\u5916\uff0c\u665a\u671f\u809d\u75c5\u7684\u8d1f\u62c5\u4e5f\u5b58\u5728\u5f88\u5927\u5dee\u5f02\u3002\u8fd9\u4e00\u8d1f\u62c5\u53d6\u51b3\u4e8e\u591a\u79cd\u56e0\u7d20\uff0c\u5305\u62ec\u6162\u6027\u4e19\u578b\u809d\u708e (HCV) \u60a3\u75c5\u7387\u3001\u611f\u67d3\u8005\u7684\u5e74\u9f84\u5206\u5e03\uff08\u53ca\u611f\u67d3\u6301\u7eed\u65f6\u95f4\uff09\u3001\u75be\u75c5\u8fdb\u5c55\u7684\u8f85\u52a9\u56e0\u7d20\uff08\u5c24\u5176\u662f\u5927\u91cf\u996e\u9152\uff09\u7684\u666e\u904d\u6027\u4ee5\u53ca\u6cbb\u7597\u5e72\u9884\u7684\u91c7\u7528\u548c\u6210\u529f\u7387\u3002\u5f15\u5165\u5047\u5b9a\u6301\u7eed\u75c5\u6bd2\u5b66\u5e94\u7b54 (SVR) \u7387 &gt;90% \u7684\u65b0\u7597\u6cd5\uff0c\u5c06\u5bf9\u9884\u8ba1\u7684\u665a\u671f\u809d\u75c5\u8d1f\u62c5\u4ea7\u751f\u9002\u5ea6\u5f71\u54cd\u3002\u589e\u5f3a\u6cbb\u7597\u6548\u679c\u5e76\u63d0\u9ad8\u6cbb\u7597\u91c7\u7528\u7387\uff0c\u5c06\u5bf9\u4eba\u7fa4\u5c42\u9762\u7684\u75be\u75c5\u8d1f\u62c5\u4ea7\u751f\u66f4\u5927\u7684\u5f71\u54cd\u3002\u7136\u800c\uff0c\u8981\u663e\u8457\u964d\u4f4e\u4e19\u578b\u809d\u708e\u75be\u75c5\u8d1f\u62c5\uff0c\u9700\u8981\u516c\u5171\u536b\u751f\u5021\u5bfc\u4ee5\u53ca\u516c\u5171\u548c\u79c1\u8425\u90e8\u95e8\u5bf9\u4e19\u578b\u809d\u708e\u5e94\u5bf9\u63aa\u65bd\u7684\u6295\u8d44\u3002<\/p>\n\n\n\n<p><strong>\u56fd\u5bb6\uff1a<\/strong> \u6fb3\u5927\u5229\u4e9a\u3001\u5965\u5730\u5229\u3001\u6bd4\u5229\u65f6\u3001\u5df4\u897f\u3001\u52a0\u62ff\u5927\u3001\u6377\u514b\u5171\u548c\u56fd\u3001\u4e39\u9ea6\u3001\u57c3\u53ca\u3001\u82f1\u56fd\u3001\u6cd5\u56fd\u3001\u5fb7\u56fd\u3001\u8461\u8404\u7259\u3001\u897f\u73ed\u7259\u3001\u745e\u5178\u3001\u745e\u58eb\u3001\u571f\u8033\u5176<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24713003\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Chronic hepatitis C virus (HCV) infection leads to liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The recent Global Burden of Disease project estimated that in 2010 among 170 million people living with chronic HCV, an estimated 483 100 people died from HCV-related liver failure or HCC. The last two decades has seen progressive improvements [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3193,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[10,12],"publication-author":[768,2293,2292],"class_list":["post-2658","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-hcv","tag-modelling","publication-author-dore-gj","publication-author-thursz-m","publication-author-ward-j"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=2658"}],"version-history":[{"count":6,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2658\/revisions"}],"predecessor-version":[{"id":7642,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2658\/revisions\/7642"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3193"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=2658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=2658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=2658"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=2658"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}