{"id":2536,"date":"2017-11-08T15:49:00","date_gmt":"2017-11-08T15:49:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2536"},"modified":"2025-01-15T03:20:23","modified_gmt":"2025-01-15T03:20:23","slug":"hepatitis-c-virus-dynamics-among-intravenous-drug-users-suggest-that-an-annual-treatment-uptake-above-10-would-eliminate-the-disease-by-2030-2","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/hepatitis-c-virus-dynamics-among-intravenous-drug-users-suggest-that-an-annual-treatment-uptake-above-10-would-eliminate-the-disease-by-2030-2\/","title":{"rendered":"\u9759\u8109\u6ce8\u5c04\u6bd2\u54c1\u4f7f\u7528\u8005\u4e2d\u7684\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u52a8\u6001\u8868\u660e\uff0c\u6bcf\u5e74\u63a5\u53d7 10% \u4ee5\u4e0a\u7684\u6cbb\u7597\u5c06\u80fd\u591f\u5728 2030 \u5e74\u524d\u6d88\u9664\u8be5\u75be\u75c5"},"content":{"rendered":"<h2 class=\"wp-block-heading\">\u6982\u62ec<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u80cc\u666f\u548c\u76ee\u6807<\/h3>\n\n\n\n<p>\u5728\u745e\u58eb\uff0c\u7531\u4e8e\u79ef\u6781\u7684\u51cf\u5bb3\u63aa\u65bd\u548c\u4eba\u53e3\u8001\u9f84\u5316\uff0c\u6ce8\u5c04\u5438\u6bd2\u8005 (PWID) \u4e2d\u4e19\u578b\u809d\u708e\u75c5\u6bd2 (HCV) \u7684\u611f\u67d3\u7387\u4e00\u76f4\u5728\u4e0b\u964d\u3002HCV \u6cbb\u7597\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u6216\u5c06\u4e3a\u76f4\u63a5\u9488\u5bf9\u9ad8\u5371\u4eba\u7fa4\u7684\u6cbb\u7597\u63d0\u4f9b\u673a\u4f1a\uff0c\u4ece\u800c\u964d\u4f4e HCV \u611f\u67d3\u7387\u5e76\u9884\u9632\u65b0\u53d1\u611f\u67d3\u3002\u4e3a\u4e86\u6307\u5bfc\u8fd9\u4e9b\u5de5\u4f5c\uff0c\u672c\u9879\u76ee\u65e8\u5728\uff1a(1) \u5229\u7528\u73b0\u6709\u7684 PWID \u6570\u636e\uff0c\u5f00\u53d1\u4e00\u4e2a\u7b80\u5355\u7684\u6a21\u578b\u6765\u4f30\u7b97\u65b0\u53d1 HCV \u611f\u67d3\u4eba\u6570\uff1b(2) \u63a2\u8ba8\u5e72\u9884\u7b56\u7565\uff08\u9884\u9632\u548c\u6cbb\u7597\uff09\u5bf9 PWID \u4e2d\u65b0\u53d1 HCV \u611f\u67d3\u4eba\u6570\u548c\u603b\u611f\u67d3\u4eba\u6570\u7684\u5f71\u54cd\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u65b9\u6cd5<\/h3>\n\n\n\n<p>\u4f7f\u7528\u52a8\u6001HCV\u4f20\u64ad\u6a21\u578b\uff0c\u6839\u636e\u6d3b\u52a8\u6027PWID\u7684\u5371\u5bb3\u51cf\u5c11\u72b6\u51b5\uff0c\u8ffd\u8e2a\u5176HCV\u53d1\u75c5\u7387\u548c\u60a3\u75c5\u7387\u3002\u7814\u7a76\u8003\u8651\u4e86\u4f7f\u7528\u65b0\u578b\u53e3\u670d\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269\u6cbb\u75971\u30015\u300110\u621615% HCV\u9633\u6027PWID\u7684\u76f8\u5bf9\u6548\u679c\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7ed3\u679c<\/h3>\n\n\n\n<p>2015 \u5e74\uff0c\u745e\u58eb\u4f30\u8ba1\u6709 10160 \u540d\u6d3b\u8dc3\u7684 PWID\uff0c\u5176\u4e2d\u8d85\u8fc7 85% \u53c2\u4e0e\u4e86\u51cf\u5c11\u5371\u5bb3\u8ba1\u5212\u3002\u5927\u7ea6 42% \u6d3b\u8dc3\u7684 PWID \u4e3a HCV-RNA+\uff0c\u6bcf\u5e74\u53d1\u751f 55 \u4f8b\u65b0\u7684\u75c5\u6bd2\u8840\u75c7\u611f\u67d3\u3002\u5230 2030 \u5e74\uff0cHCV+ PWID \u4eba\u7fa4\u9884\u8ba1\u4f1a\u51cf\u5c11 60%\u3002\u5982\u679c\u4e0d\u6539\u53d8\u884c\u4e3a\uff0c\u6240\u6709\u6cbb\u7597\u65b9\u6848\u4e0b\u7ee7\u53d1\u611f\u67d3\u7684\u6570\u91cf\u90fd\u4f1a\u589e\u52a0\u3002\u5728\u9ad8\u6c34\u5e73\u6cbb\u7597\u4e0b\uff0c\u7ee7\u53d1\u611f\u67d3\u7684\u6570\u91cf\u4f1a\u8fbe\u5230\u5cf0\u503c\uff0c\u7136\u540e\u4e0b\u964d\uff0c\u4e0e\u75c5\u6bd2\u5e93\u7684\u6d88\u8017\u76f8\u5bf9\u5e94\u3002\u5728\u745e\u58eb\uff0c\u5982\u679c 2015 \u5e74 HCV+ PWID \u4eba\u7fa4\u6bcf\u5e74\u63a5\u53d7 5% \u6cbb\u7597\uff0c\u5230 2030 \u5e74\u603b\u75c5\u4f8b\u6570\u5c06\u51cf\u5c11 95%\uff0c\u800c\u5982\u679c\u63a5\u53d7 =10% \u6cbb\u7597\uff0c\u603b\u75c5\u4f8b\u6570\u5c06\u51cf\u5c11 &gt;99%\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u7ed3\u8bba<\/h3>\n\n\n\n<p>\u53ca\u65f6\u6cbb\u7597\u6ce8\u5c04\u6bd2\u54c1\u4eba\u7fa4\u4e2d\u7684\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u5bf9\u4e8e\u964d\u4f4e\u745e\u58eb\u7684\u611f\u67d3\u7387\u548c\u9884\u9632\u65b0\u7684\u611f\u67d3\u662f\u5fc5\u8981\u7684\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>\u56fd\u5bb6\uff1a<\/strong> \u745e\u58eb<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29120012\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Background and Aims In Switzerland, the prevalence of hepatitis C virus (HCV) among people who inject drugs (PWID) has been decreasing owing to active harm reduction efforts and an aging population. Recent advances in HCV therapeutics may provide an opportunity to direct treatment to high-risk populations, with a goal of reducing HCV prevalence and [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3113,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[31,10,16],"publication-author":[488,527,917,921,918,529,523,522,922,494,920,530,919],"class_list":["post-2536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-elimination","tag-hcv","tag-pwid","publication-author-blach-s","publication-author-bruggmann-p","publication-author-deltenre-p","publication-author-fehr-j","publication-author-kouyos-r","publication-author-lavanchy-d","publication-author-mullhaupt-b","publication-author-negro-f","publication-author-rauch-a","publication-author-razavi-h","publication-author-schmid-p","publication-author-semela-d","publication-author-stoeckle-m"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=2536"}],"version-history":[{"count":7,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2536\/revisions"}],"predecessor-version":[{"id":7548,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2536\/revisions\/7548"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3113"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=2536"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=2536"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=2536"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=2536"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}