{"id":2401,"date":"2018-11-14T17:57:00","date_gmt":"2018-11-14T17:57:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2401"},"modified":"2025-01-15T02:58:26","modified_gmt":"2025-01-15T02:58:26","slug":"australia-on-track-to-achieve-who-hcv-elimination-targets-following-rapid-initial-daa-treatment-uptake-a-modeling-study","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/australia-on-track-to-achieve-who-hcv-elimination-targets-following-rapid-initial-daa-treatment-uptake-a-modeling-study\/","title":{"rendered":"\u6fb3\u5927\u5229\u4e9a\u5728\u5feb\u901f\u91c7\u7528\u521d\u59cb DAA \u6cbb\u7597\u540e\u6709\u671b\u5b9e\u73b0 WHO HCV \u6d88\u9664\u76ee\u6807\u2014\u2014\u4e00\u9879\u5efa\u6a21\u7814\u7a76"},"content":{"rendered":"<h2 class=\"wp-block-heading\">\u6982\u62ec<\/h2>\n\n\n\n<p>\u6fb3\u5927\u5229\u4e9a\u8fd1\u671f\u5f00\u59cb\u4e3a\u6240\u6709\u6210\u5e74\u6162\u6027\u4e19\u578b\u809d\u708e (HCV) \u60a3\u8005\u63d0\u4f9b\u8865\u8d34\u7684\u76f4\u63a5\u6297\u75c5\u6bd2 (DAA) \u6cbb\u7597\u3002\u57fa\u4e8e\u5feb\u901f\u7684\u63a5\u53d7\u60c5\u51b5\uff082016 \u5e74\u6709 32,600 \u4eba\u5f00\u59cb\u63a5\u53d7 DAA\uff09\uff0c\u6211\u4eec\u4f30\u7b97\u4e86\u8be5\u6cbb\u7597\u5bf9\u6fb3\u5927\u5229\u4e9a HCV \u6d41\u884c\u75c5\u5b66\u548c\u6b7b\u4ea1\u7387\u7684\u5f71\u54cd\uff0c\u5e76\u786e\u5b9a\u6fb3\u5927\u5229\u4e9a\u80fd\u5426\u5728 2030 \u5e74\u524d\u5b9e\u73b0\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u7684 HCV \u6d88\u9664\u76ee\u6807\u3002\u6211\u4eec\u4f7f\u7528\u6570\u5b66\u6a21\u578b\uff0c\u6a21\u62df\u4e86 2016 \u5e74\u81f3 2030 \u5e74\u6fb3\u5927\u5229\u4e9a DAA \u6cbb\u7597\u7684\u60b2\u89c2\u3001\u4e2d\u7b49\u548c\u4e50\u89c2\u60c5\u666f\u3002\u6211\u4eec\u5047\u8bbe\u665a\u671f\u7ea4\u7ef4\u5316\u7684\u6cbb\u7597\u548c\u68c0\u6d4b\u7387\u6700\u521d\u8f83\u9ad8\uff0c\u4e14 HCV \u4f20\u64ad\u98ce\u9669\u6c34\u5e73\u4e9a\u7fa4\u7684\u6cbb\u7597\u548c\u68c0\u6d4b\u7387\u76f8\u540c\u3002\u6211\u4eec\u8fd8\u5047\u8bbe 2016 \u5e74\u4e4b\u540e\u7684\u68c0\u6d4b\u7387\u4fdd\u6301\u4e0d\u53d8\u3002\u6211\u4eec\u5c06\u7ed3\u679c\u4e0e 2015 \u5e74\u7684\u6c34\u5e73\u548c\u53cd\u4e8b\u5b9e\uff08\u57fa\u4e8e\u5e72\u6270\u7d20\uff09\u60c5\u666f\u8fdb\u884c\u4e86\u6bd4\u8f83\u3002\u5728 2016 \u5e74\u81f3 2030 \u5e74\u671f\u95f4\uff0c\u6211\u4eec\u4f30\u8ba1\u4e2d\u7b49 DAA \u6cbb\u7597\u60c5\u666f\uff082016 \u5e74\u6cbb\u7597 32,600 \u4eba\uff1b2017 \u5e74\u6cbb\u7597 21,370 \u4eba\uff1b2018 \u5e74\u6cbb\u7597 17,100 \u4eba\uff1b2019 \u5e74\u53ca\u4ee5\u540e\uff0c\u6bcf\u5e74\u6cbb\u7597 13,680 \u4eba\uff09\u5c06\u907f\u514d 40,420 \u4f8b\u65b0\u7684 HCV \u611f\u67d3\u300113,260 \u4f8b\u809d\u810f\u76f8\u5173\u6b7b\u4ea1\uff0815,320 \u4f8b\u75c5\u6bd2\u8840\u75c7\u60a3\u8005\uff1b-2,060 \u4f8b\u6cbb\u6108\u60a3\u8005\uff09\u548c 10,730 \u4f8b HCC \u75c5\u4f8b\uff0c\u4e0e\u57fa\u4e8e IFN \u7684\u60c5\u666f\u76f8\u6bd4\uff0c\u5206\u522b\u76f8\u5f53\u4e8e\u51cf\u5c11 53%\u300163% \u548c 75%\u3002\u8be5\u6a21\u578b\u8fd8\u4f30\u8ba1\uff0c\u6fb3\u5927\u5229\u4e9a\u5c06\u57282028\u5e74\u5b9e\u73b0\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u7684\u53d1\u75c5\u7387\u548c\u6cbb\u7597\u76ee\u6807\u3002\u5b9e\u73b0\u809d\u810f\u76f8\u5173\u6b7b\u4ea1\u7387\u964d\u4f4e65%\u7684\u65f6\u95f4\uff0c\u5728\u4ec5\u6709\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u8840\u75c7\u7684\u75c5\u4f8b\uff082026\u5e74\uff09\u548c\u6240\u6709\u75c5\u4f8b\uff082047\u5e74\uff09\u4e4b\u95f4\u5dee\u5f02\u5f88\u5927\u3002\u57fa\u4e8e\u53ef\u884c\u7684\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269\uff08DAA\uff09\u6cbb\u7597\u65b9\u6848\uff0c\u5e76\u8003\u8651\u4f7f\u7528\u7387\u4e0b\u964d\uff0c\u6fb3\u5927\u5229\u4e9a\u5e94\u572810\u81f315\u5e74\u5185\u5b9e\u73b0\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u6d88\u9664\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u7684\u5173\u952e\u76ee\u6807\u3002\u665a\u671f\u809d\u75c5\u60a3\u8005\u5728DAA\u6cbb\u7597\u524d\u5242\u91cf\u589e\u52a0\uff0c\u4f7f\u5f97\u5b9e\u73b0\u809d\u810f\u76f8\u5173\u6b7b\u4ea1\u7387\u76ee\u6807\u53d8\u5f97\u56f0\u96be\u3002<\/p>\n\n\n\n<p><strong>\u56fd\u5bb6\uff1a<\/strong> \u6fb3\u5927\u5229\u4e9a<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30267593\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Subsidized direct-acting antiviral (DAA) treatment recently became available to all adults living with chronic hepatitis C (HCV) in Australia. Based on rapid uptake (32,600 people initiated DAA in 2016) we estimated the impact on HCV epidemiology and mortality in Australia and determined if Australia can meet the WHO HCV elimination targets by 2030. Using [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3193,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[10,12],"publication-author":[767,768,535,771,706,766,769,772,704,770,494],"class_list":["post-2401","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-hcv","tag-modelling","publication-author-cunningham-eb","publication-author-dore-gj","publication-author-estes-c","publication-author-gray-rt","publication-author-grebely-j","publication-author-guy-r","publication-author-hajarizadeh-b","publication-author-hcv-estimates-and-projections-reference-group","publication-author-kwon-ja","publication-author-power-c","publication-author-razavi-h"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2401","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=2401"}],"version-history":[{"count":10,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2401\/revisions"}],"predecessor-version":[{"id":7503,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2401\/revisions\/7503"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3193"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=2401"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=2401"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=2401"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=2401"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}