{"id":2394,"date":"2020-01-16T17:32:59","date_gmt":"2020-01-16T17:32:59","guid":{"rendered":"https:\/\/cdafound.org\/?p=2394"},"modified":"2025-01-14T22:16:18","modified_gmt":"2025-01-14T22:16:18","slug":"global-prevalence-of-hepatitis-c-virus-in-children-in-2018-a-modelling-study","status":"publish","type":"post","link":"https:\/\/cdafound.org\/zh\/global-prevalence-of-hepatitis-c-virus-in-children-in-2018-a-modelling-study\/","title":{"rendered":"2018\u5e74\u5168\u7403\u513f\u7ae5\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u6d41\u884c\u60c5\u51b5\uff1a\u4e00\u9879\u5efa\u6a21\u7814\u7a76"},"content":{"rendered":"<h2 class=\"wp-block-heading\" id=\"seccestitle10\">\u6982\u62ec<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">\u80cc\u666f<\/h3>\n\n\n\n<p>\u6210\u4eba\u53ca\u9ad8\u5371\u4eba\u7fa4\u7684\u4e19\u578b\u809d\u708e\u75c5\u6bd2 (HCV) \u60a3\u75c5\u7387\u4f30\u8ba1\u503c\u5df2\u5e7f\u6cdb\u53d1\u8868\uff0c\u4f46\u513f\u7ae5\u7684\u75be\u75c5\u8d1f\u62c5\u5c1a\u4e0d\u6e05\u695a\u3002\u76f4\u63a5\u6297\u75c5\u6bd2\u836f\u7269\u88ab\u8ba4\u4e3a\u662f\u6cbb\u7597\u4e19\u578b\u809d\u708e (HCV) \u7684\u9ad8\u6548\u7597\u6cd5\uff0c\u76ee\u524d\u5df2\u83b7\u6279\u7528\u4e8e\u6cbb\u75973\u5c81\u4ee5\u4e0b\u513f\u7ae5\u60a3\u8005\u3002\u9700\u8981\u5bf9\u8fd9\u4e00\u4eba\u7fa4\u8fdb\u884c\u53ef\u9760\u7684\u60a3\u75c5\u7387\u4f30\u8ba1\uff0c\u4ee5\u4fbf\u4e3a\u6269\u5927\u6cbb\u7597\u89c4\u6a21\u548c\u5236\u5b9a\u56fd\u5bb6\u6218\u7565\u63d0\u4f9b\u53c2\u8003\u3002\u672c\u5206\u6790\u7ed3\u5408\u4e86\u4ee5\u5f80\u7684\u5efa\u6a21\u6570\u636e\u4ee5\u53ca104\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u7684\u6d41\u884c\u75c5\u5b66\u7814\u7a76\uff0c\u4ee5\u4f30\u7b972018\u5e74\u5168\u7403\u513f\u7ae5\u4e19\u578b\u809d\u708e (HCV) \u60a3\u75c5\u7387\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u65b9\u6cd5<\/h3>\n\n\n\n<p>\u5728\u672c\u5efa\u6a21\u7814\u7a76\u4e2d\uff0c\u6211\u4eec\u5168\u9762\u56de\u987e\u4e86 2000 \u5e74 1 \u6708 1 \u65e5\u81f3 2019 \u5e74 3 \u6708 31 \u65e5\u671f\u95f4\u53d1\u8868\u7684\u6587\u7ae0\uff0c\u4ee5\u786e\u5b9a\u5168\u7403 249 \u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u513f\u7ae5 HCV \u60a3\u75c5\u7387\u7684\u5386\u53f2\u4f30\u8ba1\u503c\u3002\u6211\u4eec\u786e\u5b9a\u4e86 39 \u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u4e2d 0-18 \u5c81\u975e HCV \u611f\u67d3\u9ad8\u5371\u513f\u7ae5\u7684\u5df2\u53d1\u8868 HCV \u60a3\u75c5\u7387\u4f30\u8ba1\u503c\uff0c\u5e76\u5c06\u5176\u8f93\u5165\u52a8\u6001\u9a6c\u5c14\u53ef\u592b\u75be\u75c5\u8d1f\u62c5\u6a21\u578b\uff0c\u4ee5\u4f30\u7b97 2018 \u5e74\u75c5\u6bd2\u8840\u75c7 HCV \u60a3\u75c5\u7387\u3002\u5bf9\u4e8e\u5176\u4e2d 25 \u4e2a\u62e5\u6709\u5b8c\u6574\u6570\u636e\u7684\u56fd\u5bb6\uff0c\u6211\u4eec\u4f7f\u7528\u513f\u7ae5 HCV \u60a3\u75c5\u7387\u7684\u73b0\u6709\u4fe1\u606f\u5efa\u7acb\u56de\u5f52\u6a21\u578b\uff0c\u4ee5\u9884\u6d4b\u53e6\u5916 65 \u4e2a\u4ec5\u62e5\u6709\u7279\u5b9a\u56fd\u5bb6\u6216\u7279\u5b9a\u5730\u533a\u9884\u6d4b\u56e0\u5b50\u6570\u636e\u7684\u56fd\u5bb6\u548c\u5730\u533a\u7684\u513f\u79d1\u60a3\u75c5\u7387\u3002\u8003\u8651\u591a\u4e2a\u9884\u6d4b\u53d8\u91cf\uff0c\u4e3a\u6bcf\u4e2a 0 \u81f3 19 \u5c81 5 \u5e74\u513f\u79d1\u5e74\u9f84\u7ec4\u521b\u5efa\u56de\u5f52\u6a21\u578b\u3002\u4f7f\u7528\u4e86 104 \u4e2a\u6709\u6570\u636e\u7684\u56fd\u5bb6\u548c\u5730\u533a\u7684\u6570\u636e\u548c\u9884\u6d4b\u6765\u8ba1\u7b97\u5168\u7403\u75be\u75c5\u8d1f\u62c5\u533a\u57df\u7684 HCV \u60a3\u75c5\u7387\uff0c\u7136\u540e\u5c06\u5176\u5e94\u7528\u4e8e\u5176\u4f59 145 \u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u4ee5\u751f\u6210\u5168\u7403\u4f30\u8ba1\u503c\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u53d1\u73b0<\/h3>\n\n\n\n<p>\u5168\u7403 0-18 \u5c81\u513f\u7ae5\u75c5\u6bd2\u8840\u75c7\u60a3\u75c5\u7387\u4f30\u8ba1\u4e3a 0.13%\uff0895% \u4e0d\u786e\u5b9a\u533a\u95f4 0.08\u20130.16\uff09\uff0c\u76f8\u5f53\u4e8e 2018 \u5e74\u6709 326 \u4e07\uff082.07\u20133.90\uff09\u540d\u513f\u7ae5\u611f\u67d3 HCV\u3002\u6240\u6709\u56fd\u5bb6\u548c\u5730\u533a\u7684 HCV \u60a3\u75c5\u7387\u90fd\u968f\u7740\u5e74\u9f84\u7684\u589e\u957f\u800c\u589e\u52a0\u3002\u80b2\u9f84\u5987\u5973\u7684 HCV \u60a3\u75c5\u7387\u662f 0-4 \u5c81\u513f\u7ae5 HCV \u60a3\u75c5\u7387\u7684\u6700\u5f3a\u9884\u6d4b\u56e0\u7d20\uff08p&lt;0.0001\uff09\u3002\u6210\u4eba HCV \u60a3\u75c5\u7387\u4e0e 5-19 \u5c81\u513f\u7ae5\u7684 HCV \u60a3\u75c5\u7387\u663e\u8457\u76f8\u5173\uff08p&lt;0.0001\uff09\uff0c\u6ce8\u5c04\u6bd2\u54c1\u4eba\u7fa4\u7684 HCV \u611f\u67d3\u6bd4\u4f8b\u4e0e 15-19 \u5c81\u513f\u7ae5\u7684 HCV \u60a3\u75c5\u7387\u663e\u8457\u76f8\u5173\uff08p=0.036\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u89e3\u91ca<\/h3>\n\n\n\n<p>\u5927\u591a\u6570\u5173\u4e8e\u513f\u7ae5\u4e19\u578b\u809d\u708e\uff08HCV\uff09\u60a3\u75c5\u7387\u7684\u7814\u7a76\u90fd\u96c6\u4e2d\u5728\u9ad8\u5371\u4eba\u7fa4\u548c\u9ad8\u5ea6\u6d41\u884c\u7684\u5730\u533a\u3002\u6211\u4eec\u7684\u5206\u6790\u63d0\u4f9b\u4e86\u5168\u7403\u513f\u7ae5\u4eba\u7fa4\u4e2d\u4e19\u578b\u809d\u708e\uff08HCV\uff09\u7684\u60a3\u75c5\u7387\u4f30\u8ba1\u503c\u3002\u4e0e\u6210\u4eba\u60a3\u8005\u76f8\u6bd4\uff0c\u513f\u7ae5\u60a3\u8005\u7684\u6cbb\u7597\u9700\u8981\u4e0d\u540c\u7684\u4e34\u5e8a\u548c\u4eba\u7fa4\u5065\u5eb7\u7ba1\u7406\u4f18\u5316\u3002\u7531\u4e8e\u8fd9\u79cd\u5f02\u8d28\u6027\uff0c\u9488\u5bf9\u7279\u5b9a\u56fd\u5bb6\u6216\u5730\u533a\u4ee5\u53ca\u7279\u5b9a\u5e74\u9f84\u7684HCV\u60a3\u75c5\u7387\u4f30\u8ba1\u503c\u53ef\u4ee5\u5e2e\u52a9\u56fd\u5bb6\u548c\u5730\u533a\u6539\u8fdb\u56fd\u5bb6HCV\u6d88\u9664\u7b56\u7565\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u8d44\u91d1<\/h3>\n\n\n\n<p>\u5409\u5229\u5fb7\u79d1\u5b66\u516c\u53f8\u3001\u7ea6\u7ff0\u00b7C\u00b7\u9a6c\u4e01\u57fa\u91d1\u4f1a\u548c\u79c1\u4eba\u6350\u52a9\u8005\u3002<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31954439\/\" style=\"border-radius:6px;color:#951b23\" target=\"_blank\" rel=\"noreferrer noopener\">\u9605\u8bfb\u5b8c\u6574\u62a5\u544a<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Background Hepatitis C virus (HCV) prevalence estimates for adults and high-risk groups have been widely published, but the disease burden in children is poorly understood. Direct-acting antiviral drugs, which are considered to be highly effective curative therapies for HCV, are now approved for paediatric patients as young as 3 years. Reliable prevalence estimates for [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3107,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[13,10,12,11],"publication-author":[488,670,742,740,650,744,535,542,739,669,743,494,497,664,741,653],"class_list":["post-2394","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-global","tag-hcv","tag-modelling","tag-pediatric","publication-author-blach-s","publication-author-cai-z","publication-author-coleman-s-2","publication-author-depaola-m","publication-author-dugan-e-2","publication-author-el-sayed-mh","publication-author-estes-c","publication-author-gamkrelidze-i","publication-author-jerabek-k","publication-author-ma-s","publication-author-montoya-s","publication-author-razavi-h","publication-author-razavi-shearer-d","publication-author-razavi-shearer-k","publication-author-robbins-scott-s","publication-author-schmelzer-j"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/comments?post=2394"}],"version-history":[{"count":12,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2394\/revisions"}],"predecessor-version":[{"id":7485,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/posts\/2394\/revisions\/7485"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media\/3107"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/media?parent=2394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/categories?post=2394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/tags?post=2394"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/zh\/wp-json\/wp\/v2\/publication-author?post=2394"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}