{"id":9126,"date":"2025-07-01T02:04:00","date_gmt":"2025-07-01T02:04:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=9126"},"modified":"2026-05-29T03:37:51","modified_gmt":"2026-05-29T03:37:51","slug":"modeling-the-health-and-economic-impact-of-pharmacologic-therapies-for-masld-in-the-united-states","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/modeling-the-health-and-economic-impact-of-pharmacologic-therapies-for-masld-in-the-united-states\/","title":{"rendered":"Mod\u00e9lisation de l&#039;impact sanitaire et \u00e9conomique des traitements pharmacologiques de la MASLD aux \u00c9tats-Unis"},"content":{"rendered":"<h2 class=\"wp-block-heading\" id=\"summary\">R\u00e9sum\u00e9<\/h2>\n\n\n\n<p>La st\u00e9atose h\u00e9patique associ\u00e9e \u00e0 un dysfonctionnement m\u00e9tabolique (MASLD), cause la plus fr\u00e9quente et dont la progression est la plus rapide parmi les maladies h\u00e9patiques chroniques, engendre des co\u00fbts de sant\u00e9 consid\u00e9rables. Face \u00e0 l&#039;augmentation de la charge de morbidit\u00e9 et des co\u00fbts associ\u00e9s, des traitements pharmacologiques capables de stopper la progression de la fibrose li\u00e9e \u00e0 la MASLD sont en passe de devenir r\u00e9alit\u00e9. La mod\u00e9lisation de l&#039;impact d&#039;un tel traitement, envisag\u00e9 sous diff\u00e9rents sc\u00e9narios, sur la progression de la maladie permet de mieux comprendre les principaux facteurs \u00e0 l&#039;origine de la MASLD et les co\u00fbts qui y sont associ\u00e9s. Ces donn\u00e9es devraient contribuer \u00e0 l&#039;\u00e9laboration de politiques et de pratiques optimales pour r\u00e9duire le fardeau de la MASLD.<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/cdafound.org\/wp-content\/uploads\/2026\/05\/Wallace-2025-MASH-treatment-impact-US.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary Metabolic dysfunction-associated steatotic liver disease (MASLD), the most rapidly increasing and prevalent cause of chronic liver disease, is associated with substantial healthcare costs. As disease burden and costs mount, pharmacologic therapy which halts MASLD fibrosis progression is coming to fruition. Modeling the impact on disease progression of a hypothetical pharmacologic therapy which halts MASLD [&hellip;]<\/p>\n","protected":false},"author":939,"featured_media":5127,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[32,2688,12],"publication-author":[2676,2675,95,97,92],"class_list":["post-9126","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-economic-impact","tag-masld","tag-modelling","publication-author-arun-j-sanyal","publication-author-carolyn-wallace","publication-author-chris-estes","publication-author-homie-razavi","publication-author-ivane-gamkrelidze"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/9126","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/939"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=9126"}],"version-history":[{"count":2,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/9126\/revisions"}],"predecessor-version":[{"id":9129,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/9126\/revisions\/9129"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/5127"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=9126"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=9126"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=9126"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/publication-author?post=9126"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}