{"id":3078,"date":"2018-06-08T23:27:00","date_gmt":"2018-06-08T23:27:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=3078"},"modified":"2025-01-15T03:13:42","modified_gmt":"2025-01-15T03:13:42","slug":"modeling-nafld-disease-burden-in-china-france-germany-italy-japan-spain-united-kingdom-and-united-states-for-the-period-2016-2030","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/modeling-nafld-disease-burden-in-china-france-germany-italy-japan-spain-united-kingdom-and-united-states-for-the-period-2016-2030\/","title":{"rendered":"Mod\u00e9lisation de la charge de morbidit\u00e9 de la NAFLD en Chine, en France, en Allemagne, en Italie, au Japon, en Espagne, au Royaume-Uni et aux \u00c9tats-Unis pour la p\u00e9riode 2016-2030"},"content":{"rendered":"

R\u00e9sum\u00e9<\/h2>\n\n\n\n

Contexte et objectifs<\/h3>\n\n\n\n

La st\u00e9atose h\u00e9patique non alcoolique (NAFLD) et la st\u00e9atoh\u00e9patite non alcoolique (NASH) sont de plus en plus une cause de cirrhose et de carcinome h\u00e9patocellulaire dans le monde. On s'attend \u00e0 ce que ce fardeau augmente \u00e0 mesure que les \u00e9pid\u00e9mies d'ob\u00e9sit\u00e9, de diab\u00e8te et de syndrome m\u00e9tabolique continuent de cro\u00eetre. Le but de cette analyse \u00e9tait d'utiliser un mod\u00e8le de Markov pour pr\u00e9voir la charge de morbidit\u00e9 de la NAFLD en utilisant les donn\u00e9es actuellement disponibles.<\/p>\n\n\n\n

M\u00e9thodes<\/h3>\n\n\n\n

Un mod\u00e8le a \u00e9t\u00e9 utilis\u00e9 pour estimer la progression de la NAFLD et de la NASH dans huit pays sur la base de donn\u00e9es sur la pr\u00e9valence de l'ob\u00e9sit\u00e9 chez l'adulte et du diab\u00e8te sucr\u00e9 de type 2 (DM). Des estimations publi\u00e9es et un consensus d'experts ont \u00e9t\u00e9 utilis\u00e9s pour construire et valider les projections du mod\u00e8le.<\/p>\n\n\n\n

R\u00e9sultats<\/h3>\n\n\n\n

Si l'ob\u00e9sit\u00e9 et la DM se stabilisent \u00e0 l'avenir, nous pr\u00e9voyons une croissance modeste du nombre total de cas de NAFLD (0-30%), entre 2016 et 2030, avec la croissance la plus \u00e9lev\u00e9e en Chine en raison de l'urbanisation et la croissance la plus faible au Japon en cons\u00e9quence d'une population en d\u00e9croissance. Cependant, dans le m\u00eame temps, la pr\u00e9valence de la NASH augmentera de 15 \u00e0 56%, tandis que la mortalit\u00e9 h\u00e9patique et la maladie h\u00e9patique avanc\u00e9e feront plus que doubler en raison du vieillissement \/ de l'augmentation de la population.<\/p>\n\n\n\n

Conclusions<\/h3>\n\n\n\n

La NAFLD et la NASH repr\u00e9sentent un probl\u00e8me de sant\u00e9 publique important et croissant et des efforts sont n\u00e9cessaires pour comprendre cette \u00e9pid\u00e9mie et att\u00e9nuer la charge de morbidit\u00e9. Si l'ob\u00e9sit\u00e9 et la DM continuent d'augmenter aux taux actuels et historiques, la pr\u00e9valence de la NAFLD et de la NASH devrait augmenter. \u00c9tant donn\u00e9 que les deux sont r\u00e9versibles, des campagnes de sant\u00e9 publique visent \u00e0 accro\u00eetre la sensibilisation et le diagnostic, et \u00e0 promouvoir l'alimentation et l'exercice.<\/p>\n\n\n\n

Pays: Chine, France, Allemagne, Italie, Japon, Espagne, Royaume-Uni, \u00c9tats-Unis<\/p>\n\n

\n
Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Summary Background & Aims Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are increasingly a cause of cirrhosis and hepatocellular carcinoma globally. This burden is expected to increase as epidemics of obesity, diabetes and metabolic syndrome continue to grow. The goal of this analysis was to use a Markov model to forecast NAFLD disease […]<\/p>\n","protected":false},"author":24,"featured_media":3325,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[24],"publication-author":[521,870,876,747,868,502,671,878,875,879,535,877,668,881,499,872,873,509,867,522,721,503,494,871,869,874,516,882,880,883,616],"class_list":["post-3078","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-nafld","publication-author-anstee-qm","publication-author-arias-loste-mt","publication-author-bantel-h","publication-author-bellentani-s","publication-author-caballeria-j","publication-author-colombo-m","publication-author-craxi-a","publication-author-crespo-j","publication-author-day-cp","publication-author-eguchi-y","publication-author-estes-c","publication-author-geier-a","publication-author-kondili-la","publication-author-kroy-dc","publication-author-lazarus-jv","publication-author-loomba-r","publication-author-manns-mp","publication-author-marchesini-g","publication-author-nakajima-a","publication-author-negro-f","publication-author-petta-s","publication-author-ratziu-v","publication-author-razavi-h","publication-author-romero-gomez-m-2","publication-author-sanyal-a","publication-author-schattenberg-jm","publication-author-tacke-f","publication-author-tanaka-j","publication-author-trautwein-c","publication-author-wei-l","publication-author-zeuzem-s"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/3078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=3078"}],"version-history":[{"count":5,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/3078\/revisions"}],"predecessor-version":[{"id":7536,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/3078\/revisions\/7536"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/3325"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=3078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=3078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=3078"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/publication-author?post=3078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}