{"id":2664,"date":"2014-05-05T21:40:00","date_gmt":"2014-05-05T21:40:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2664"},"modified":"2025-01-16T15:56:17","modified_gmt":"2025-01-16T15:56:17","slug":"strategies-to-manage-hepatitis-c-virus-hcv-disease-burden","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/strategies-to-manage-hepatitis-c-virus-hcv-disease-burden\/","title":{"rendered":"Strat\u00e9gies pour g\u00e9rer le fardeau de la maladie du virus de l&#039;h\u00e9patite C (VHC)"},"content":{"rendered":"<h2 class=\"wp-block-heading\">R\u00e9sum\u00e9<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Le nombre d\u2019infections par le virus de l\u2019h\u00e9patite C (VHC) devrait diminuer tandis que le nombre de personnes atteintes d\u2019une maladie h\u00e9patique avanc\u00e9e augmentera. Une approche de mod\u00e9lisation a \u00e9t\u00e9 utilis\u00e9e pour pr\u00e9voir deux sc\u00e9narios de traitement\u00a0: (i) l\u2019impact d\u2019une efficacit\u00e9 accrue du traitement tout en maintenant constant le nombre de patients trait\u00e9s et (ii) une augmentation de l\u2019efficacit\u00e9 et du taux de traitement. Cette analyse sugg\u00e8re qu&#039;un diagnostic et un traitement r\u00e9ussis d&#039;une petite proportion de patients peuvent contribuer de mani\u00e8re significative \u00e0 la r\u00e9duction de la charge de morbidit\u00e9 dans les pays \u00e9tudi\u00e9s. La r\u00e9duction la plus importante de la morbidit\u00e9 et de la mortalit\u00e9 li\u00e9es au VHC se produit lorsque l\u2019augmentation du traitement est combin\u00e9e \u00e0 des th\u00e9rapies plus efficaces, g\u00e9n\u00e9ralement associ\u00e9es \u00e0 un diagnostic accru. Avec un taux de traitement d&#039;environ 10%, cette analyse sugg\u00e8re qu&#039;il est possible de parvenir \u00e0 l&#039;\u00e9limination du VHC (d\u00e9finie comme une baisse &gt;90% du nombre total d&#039;infections d&#039;ici 2030). Cependant, pour la plupart des pays pr\u00e9sent\u00e9s, cela n\u00e9cessitera une multiplication par 3 \u00e0 5 du diagnostic et\/ou du traitement. Il sera donc essentiel de renforcer les capacit\u00e9s des prestataires de sant\u00e9 publique et des prestataires cliniques pour am\u00e9liorer le diagnostic et le traitement.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Des pays:<\/strong> Australie, Autriche, Belgique, Br\u00e9sil, R\u00e9publique tch\u00e8que, Danemark, \u00c9gypte, Angleterre, France, Allemagne, Portugal, Espagne, Su\u00e8de, Suisse, Turquie<\/p>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-text-color wp-element-button\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24713006\" target=\"_blank\" rel=\"noreferrer noopener\">Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Summary The number of hepatitis C virus (HCV) infections is projected to decline while those with advanced liver disease will increase. A modeling approach was used to forecast two treatment scenarios: (i) the impact of increased treatment efficacy while keeping the number of treated patients constant and (ii) increasing efficacy and treatment rate. This analysis [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":3193,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[10],"publication-author":[2281,586,2289,2290,525,2249,1065,2280,527,1063,2286,1064,2100,2282,2276,2099,2275,2181,768,2243,583,863,1042,520,535,2178,2260,755,2097,2283,1071,2278,2284,2285,1141,2279,2288,2270,2244,2266,2271,2261,584,2268,884,2274,711,2269,1134,529,1069,2273,697,2251,2272,2095,523,2248,522,2277,1039,2183,2257,695,494,2256,735,2180,2253,2182,2252,2255,530,2250,2259,1078,2254,1136,2258,2184,2262,895,2263,1132,1135,2265,667,896,2264,2287,2240,2102,2267],"class_list":["post-2664","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-hcv","publication-author-akarca-u","publication-author-aleman-s","publication-author-balik-i-2","publication-author-berg-t","publication-author-bihl-f","publication-author-bilodeau-m","publication-author-blasco-aj","publication-author-brandao-mello-ce-2","publication-author-bruggmann-p","publication-author-buti-m","publication-author-calinas-f","publication-author-calleja-jl","publication-author-cheinquer-h","publication-author-christensen-pb","publication-author-clausen-m","publication-author-coelho-hs","publication-author-cornberg-m","publication-author-cramp-me","publication-author-dore-gj","publication-author-doss-w","publication-author-duberg-as","publication-author-el-sayed-mh-2","publication-author-ergor-g","publication-author-esmat-g","publication-author-estes-c","publication-author-falconer-k","publication-author-felix-j","publication-author-ferraz-ml","publication-author-ferreira-pr","publication-author-frankova-s","publication-author-garcia-samaniego-j","publication-author-gerstoft-j","publication-author-giria-ja","publication-author-goncales-fl-jr","publication-author-gower-e","publication-author-gschwantler-m","publication-author-guimaraes-pessoa-m","publication-author-hezode-c","publication-author-hindman-sj","publication-author-hofer-h","publication-author-husa-p","publication-author-idilman-r","publication-author-kaberg-m","publication-author-kaita-kd","publication-author-kautz-a","publication-author-kaymakoglu-s","publication-author-krajden-m","publication-author-krarup-h","publication-author-laleman-w","publication-author-lavanchy-d","publication-author-lazaro-p","publication-author-marinho-rt","publication-author-marotta-p","publication-author-mauss-s","publication-author-mendes-correa-mc-2","publication-author-moreno-c","publication-author-mullhaupt-b","publication-author-myers-rp","publication-author-negro-f","publication-author-nemecek-v","publication-author-ormeci-n","publication-author-parkes-j","publication-author-peltekian-km","publication-author-ramji-a","publication-author-razavi-h","publication-author-reis-n","publication-author-roberts-sk","publication-author-rosenberg-wm","publication-author-roudot-thoraval-f","publication-author-ryder-sd","publication-author-sarmento-castro-r","publication-author-sarrazin-c","publication-author-semela-d","publication-author-sherman-m","publication-author-shiha-ge","publication-author-sievert-w","publication-author-sperl-j","publication-author-starkel-p","publication-author-stauber-re","publication-author-thompson-aj","publication-author-urbanek-p","publication-author-van-damme-p","publication-author-van-thiel-i","publication-author-van-vlierberghe-h","publication-author-vandijck-d","publication-author-vogel-w","publication-author-waked-i","publication-author-wedemeyer-h","publication-author-weis-n","publication-author-wiegand-j","publication-author-yosry-a","publication-author-zekry-a","publication-author-ovrehus-al"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=2664"}],"version-history":[{"count":6,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2664\/revisions"}],"predecessor-version":[{"id":7638,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2664\/revisions\/7638"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/3193"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=2664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=2664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=2664"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/c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