{"id":2642,"date":"2015-07-22T20:36:00","date_gmt":"2015-07-22T20:36:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2642"},"modified":"2025-01-16T15:31:50","modified_gmt":"2025-01-16T15:31:50","slug":"economic-burden-of-hepatitis-c-in-egypt-the-future-impact-of-highly-effective-therapies","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/economic-burden-of-hepatitis-c-in-egypt-the-future-impact-of-highly-effective-therapies\/","title":{"rendered":"Fardeau \u00e9conomique de l'h\u00e9patite C en \u00c9gypte: l'impact futur de th\u00e9rapies hautement efficaces"},"content":{"rendered":"

R\u00e9sum\u00e9<\/h2>\n\n\n\n

Arri\u00e8re-plan<\/h3>\n\n\n\n

La pr\u00e9valence de l'infection par le virus de l'h\u00e9patite C (VHC) en \u00c9gypte est la plus \u00e9lev\u00e9e au monde, mais le fardeau \u00e9conomique total n'a pas \u00e9t\u00e9 quantifi\u00e9. Une meilleure compr\u00e9hension des co\u00fbts et de l'impact des strat\u00e9gies de traitement permettra une meilleure allocation des ressources pour r\u00e9duire la maladie \u00e0 VHC et le fardeau \u00e9conomique.<\/p>\n\n\n\n

Objectif<\/h3>\n\n\n\n

Une approche de mod\u00e9lisation a \u00e9t\u00e9 utilis\u00e9e pour quantifier la population actuelle infect\u00e9e par le VHC, la progression future de la maladie et les co\u00fbts associ\u00e9s en \u00c9gypte.<\/p>\n\n\n\n

M\u00e9thodes<\/h3>\n\n\n\n

Les co\u00fbts directs des soins de sant\u00e9 ont \u00e9t\u00e9 calcul\u00e9s \u00e0 partir d'un h\u00f4pital repr\u00e9sentatif au niveau national et un mod\u00e8le d'ann\u00e9e de vie corrig\u00e9e de l'incapacit\u00e9 (DALY) a \u00e9t\u00e9 utilis\u00e9 avec une valeur mon\u00e9taire attribu\u00e9e aux ann\u00e9es de vie perdues. Trois sc\u00e9narios ont \u00e9t\u00e9 envisag\u00e9s: (i) Sc\u00e9nario de traitement historique: 50% SVR; 65 000 trait\u00e9s annuellement, (ii) Sc\u00e9nario de traitement actuel: 90% r\u00e9ponse virologique soutenue (RVS); 65 000 trait\u00e9s annuellement, (iii) Sc\u00e9nario de traitement accru: 90% SVR; 325000 trait\u00e9s annuellement d'ici 2018.<\/p>\n\n\n\n

R\u00e9sultats<\/h3>\n\n\n\n

Les AVCI cumul\u00e9es (2015-2030) dans le sc\u00e9nario 1 ont \u00e9t\u00e9 estim\u00e9es \u00e0 7,88 millions et les co\u00fbts cumul\u00e9s \u00e0 $89,07 milliards. Les DALY annuels ont augment\u00e9 de 16% entre 2015 et 2030 tandis que les co\u00fbts annuels ont plus que doubl\u00e9. Le sc\u00e9nario 2 a r\u00e9duit les DALY et les co\u00fbts cumulatifs de 7% et 4%, respectivement. Dans le sc\u00e9nario 3, les co\u00fbts totaux ont diminu\u00e9 de 73% \u00e0 $1047 millions en 2015-2030. Par rapport au sc\u00e9nario 1, les AVCI et les co\u00fbts cumulatifs ont diminu\u00e9 respectivement de 37% et 35%.<\/p>\n\n\n\n

Conclusions<\/h3>\n\n\n\n

Il s'agit de la premi\u00e8re estimation du fardeau \u00e9conomique total du VHC en \u00c9gypte. Des mesures extraordinaires sont n\u00e9cessaires pour r\u00e9duire consid\u00e9rablement la maladie \u00e0 VHC et le fardeau des co\u00fbts. Avec les th\u00e9rapies plus r\u00e9centes, les strat\u00e9gies de r\u00e9duction du fardeau de la maladie sont r\u00e9alisables et rentables.<\/p>\n\n\n\n

Des pays: <\/strong>Egypte<\/p>\n\n

\n
Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Summary Background The prevalence of hepatitis C virus (HCV) infection in Egypt is the highest in the world, yet the total economic burden has not been quantified. Improved understanding of costs and the impact of treatment strategies will provide for better allocation of resources to reduce HCV disease and economic burden. Aim A modelling approach […]<\/p>\n","protected":false},"author":24,"featured_media":3187,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[32,10],"publication-author":[2088,2089,2092,2094,535,2090,2091,494,667,2093],"class_list":["post-2642","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-economic-impact","tag-hcv","publication-author-abdel-kareem-m","publication-author-abdel-razek-w","publication-author-abdel-sameea-e","publication-author-abuzeid-m","publication-author-estes-c","publication-author-gomaa-a","publication-author-osman-w","publication-author-razavi-h","publication-author-waked-i","publication-author-zaghla-h"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=2642"}],"version-history":[{"count":6,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2642\/revisions"}],"predecessor-version":[{"id":7602,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2642\/revisions\/7602"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/3187"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=2642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=2642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=2642"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/publication-author?post=2642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}