{"id":2530,"date":"2018-07-12T15:29:00","date_gmt":"2018-07-12T15:29:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2530"},"modified":"2025-01-15T03:11:48","modified_gmt":"2025-01-15T03:11:48","slug":"disease-burden-of-hepatitis-c-in-the-austrian-state-of-tyrol-epidemiological-data-and-model-analysis-to-achieve-elimination-by-2030","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/disease-burden-of-hepatitis-c-in-the-austrian-state-of-tyrol-epidemiological-data-and-model-analysis-to-achieve-elimination-by-2030\/","title":{"rendered":"Fardeau de la maladie de l'h\u00e9patite C dans l'\u00c9tat autrichien du Tyrol - Donn\u00e9es \u00e9pid\u00e9miologiques et analyse de mod\u00e8les pour parvenir \u00e0 l'\u00e9limination d'ici 2030"},"content":{"rendered":"

R\u00e9sum\u00e9<\/h2>\n\n\n\n

Arri\u00e8re-plan<\/h3>\n\n\n\n

En 2016, l'Organisation mondiale de la sant\u00e9 (OMS) et la 69e Assembl\u00e9e mondiale de la sant\u00e9 ont approuv\u00e9 la premi\u00e8re strat\u00e9gie mondiale du secteur de la sant\u00e9 (GHSS) sur l'h\u00e9patite virale dans le but d'\u00e9liminer les infections par le virus de l'h\u00e9patite C (VHC) dans le monde. L'objectif est une r\u00e9duction de 90% des nouvelles infections et de 65% des d\u00e9c\u00e8s li\u00e9s au VHC d'ici 2030.<\/p>\n\n\n\n

Objectif<\/h3>\n\n\n\n

Cette \u00e9tude rend compte de l'\u00e9pid\u00e9miologie des infections par le VHC dans l'\u00c9tat autrichien du Tyrol (population totale de 750000 habitants) et utilise un mod\u00e8le pr\u00e9dictif pour identifier comment la strat\u00e9gie de l'OMS pour l'\u00e9limination du VHC peut \u00eatre r\u00e9alis\u00e9e.<\/p>\n\n\n\n

M\u00e9thodes<\/h3>\n\n\n\n

Nous avons d\u00e9velopp\u00e9 un mod\u00e8le r\u00e9gional de charge de morbidit\u00e9 bas\u00e9 sur les donn\u00e9es de diagnostic locales observ\u00e9es de 2001 \u00e0 2016. Des sc\u00e9narios ont \u00e9t\u00e9 d\u00e9velopp\u00e9s pour \u00e9valuer l'impact du diagnostic et du traitement sur les r\u00e9sultats li\u00e9s au VHC (pr\u00e9valence vir\u00e9mique, cirrhose d\u00e9compens\u00e9e, carcinome h\u00e9patocellulaire et d\u00e9c\u00e8s li\u00e9s au foie) de 2015 \u00e0 2030.<\/p>\n\n\n\n

R\u00e9sultats<\/h3>\n\n\n\n

Au cours des 15 derni\u00e8res ann\u00e9es, 1 721 patients vivant au Tyrol ont re\u00e7u un diagnostic d'infection chronique par le VHC. Si l'on tient compte du vieillissement, de la mortalit\u00e9 et du traitement, on estime \u00e0 2 043 infections vir\u00e9miques le VHC en 2016, dont 1136 cas ont \u00e9t\u00e9 diagnostiqu\u00e9s. Un mod\u00e8le de r\u00e9f\u00e9rence pr\u00e9dit une diminution de 588 cas de VHC de 2015 \u00e0 2030, ce qui ne se traduirait pas par la r\u00e9duction significative des infections n\u00e9cessaire pour atteindre les recommandations sanitaires mondiales de l'OMS. Au total, 1 843 personnes infect\u00e9es doivent \u00eatre identifi\u00e9es et trait\u00e9es pour atteindre les objectifs de l'OMS d'ici 2030 (1 254 cas \u00e9vit\u00e9s par rapport au mod\u00e8le de r\u00e9f\u00e9rence). La mise en \u0153uvre de cette strat\u00e9gie \u00e9viterait 523 nouvelles infections par le VHC et r\u00e9duirait la mortalit\u00e9 li\u00e9e au VHC de 73%.<\/p>\n\n\n\n

Conclusion<\/h3>\n\n\n\n

L\u2019\u00e9limination du VHC et la r\u00e9duction de la mortalit\u00e9 associ\u00e9e \u00e0 l\u2019h\u00e9patite C >65% sont possibles au Tyrol, mais n\u00e9cessitent une augmentation significative des nouveaux diagnostics et du taux de traitement. Le mod\u00e8le pr\u00e9sent\u00e9 dans cette \u00e9tude pourrait servir d\u2019exemple \u00e0 d\u2019autres r\u00e9gions pour pr\u00e9dire de mani\u00e8re fiable la charge de morbidit\u00e9 r\u00e9gionale et estimer comment les objectifs de l\u2019OMS peuvent \u00eatre atteints \u00e0 l\u2019avenir.<\/p>\n\n\n\n

Des pays:<\/strong> L'Autriche<\/p>\n\n

\n
Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Summary Background In 2016, the World Health Organization (WHO) and 69th World Health Assembly approved the first global health sector strategy (GHSS) on viral hepatitis with the goal to eliminate hepatitis C virus (HCV) infections worldwide. The aim is a 90% reduction of new infections and 65% reduction of HCV-related deaths by 2030. Aim This […]<\/p>\n","protected":false},"author":24,"featured_media":3237,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[31,10,12],"publication-author":[847,488,853,856,851,850,849,494,848,855,852,854,857],"class_list":["post-2530","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-elimination","tag-hcv","tag-modelling","publication-author-al-zoairy-r","publication-author-blach-s","publication-author-brandon-s","publication-author-dorn-l","publication-author-effenberger-m","publication-author-finkenstedt-a","publication-author-graziadei-i","publication-author-razavi-h","publication-author-sarcletti-m","publication-author-schaefer-b","publication-author-tilg-h","publication-author-viveiros-a","publication-author-zoller-h"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=2530"}],"version-history":[{"count":8,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2530\/revisions"}],"predecessor-version":[{"id":7533,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2530\/revisions\/7533"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/3237"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=2530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=2530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=2530"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/publication-author?post=2530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}