{"id":2414,"date":"2019-05-27T19:25:00","date_gmt":"2019-05-27T19:25:00","guid":{"rendered":"https:\/\/cdafound.org\/?p=2414"},"modified":"2025-01-14T22:17:37","modified_gmt":"2025-01-14T22:17:37","slug":"hepatitis-c-disease-burden-and-strategies-for-elimination-by-2030-in-brazil-a-mathematical-modeling-approach","status":"publish","type":"post","link":"https:\/\/cdafound.org\/fr\/hepatitis-c-disease-burden-and-strategies-for-elimination-by-2030-in-brazil-a-mathematical-modeling-approach\/","title":{"rendered":"Fardeau de l'h\u00e9patite C et strat\u00e9gies d'\u00e9limination d'ici 2030 au Br\u00e9sil. Une approche de mod\u00e9lisation math\u00e9matique"},"content":{"rendered":"

R\u00e9sum\u00e9<\/h2>\n\n\n\n

Introduction et objectif<\/h3>\n\n\n\n

L'h\u00e9patite C est un d\u00e9fi majeur pour la sant\u00e9 publique au Br\u00e9sil. L'objectif de cet article \u00e9tait de d\u00e9crire la strat\u00e9gie br\u00e9silienne de l'h\u00e9patite C pour atteindre l'objectif d'\u00e9limination \u00e0 l'horizon 2030 propos\u00e9 par l'Organisation mondiale de la sant\u00e9 (OMS).<\/p>\n\n\n\n

M\u00e9thodes<\/h3>\n\n\n\n

Une approche de mod\u00e9lisation math\u00e9matique a \u00e9t\u00e9 utilis\u00e9e pour estimer la population br\u00e9silienne actuelle infect\u00e9e par le VHC et pour \u00e9valuer les co\u00fbts relatifs de deux sc\u00e9narios diff\u00e9rents pour faire face \u00e0 la charge de morbidit\u00e9 par le VHC au Br\u00e9sil: (1) si aucun autre changement n'est apport\u00e9 au programme de traitement du VHC au Br\u00e9sil. ; (2) o\u00f9 les objectifs de l'OMS pour l'\u00e9limination \u00e0 l'horizon 2030 sont atteints gr\u00e2ce \u00e0 des efforts de diagnostic et de traitement culminant avant 2024.<\/p>\n\n\n\n

R\u00e9sultats<\/h3>\n\n\n\n

Une pr\u00e9valence anti-VHC de 0,53% a \u00e9t\u00e9 calcul\u00e9e pour la population totale. Il a \u00e9t\u00e9 estim\u00e9 que le nombre d'individus VHC-ARN + au Br\u00e9sil en 2017 \u00e9tait de 632000 (0,31% de la population). Une intensification du traitement et du diagnostic au fil du temps sera n\u00e9cessaire pour atteindre les objectifs de l'OMS \u00e0 partir de 2018. Les co\u00fbts directs (diagnostics, traitements et soins de sant\u00e9) devraient augmenter consid\u00e9rablement au cours de l'intensification du traitement et du diagnostic au cours des premi\u00e8res ann\u00e9es. du sc\u00e9nario d'intervention, mais ensuite tomber en dessous du sc\u00e9nario de base sur une base annuelle d'ici 2025-2036, une fois le VHC \u00e9limin\u00e9, en raison des \u00e9conomies r\u00e9alis\u00e9es par le secteur de la sant\u00e9 gr\u00e2ce \u00e0 la pr\u00e9vention de la morbidit\u00e9 et de la mortalit\u00e9 h\u00e9patiques li\u00e9es au VHC.<\/p>\n\n\n\n

Conclusion<\/h3>\n\n\n\n

Atteindre les objectifs de l'OMS est techniquement faisable au Br\u00e9sil avec une intensification du traitement et du diagnostic au fil du temps, \u00e0 partir de 2018. Cependant, l'\u00e9limination de l'h\u00e9patite C n\u00e9cessite des changements de politique pour intensifier consid\u00e9rablement la pr\u00e9vention, le d\u00e9pistage et le traitement du VHC, en collaboration avec le public. le plaidoyer en mati\u00e8re de sant\u00e9 pour sensibiliser les populations touch\u00e9es et les prestataires de soins de sant\u00e9.<\/p>\n\n\n\n

Des pays:<\/strong> Br\u00e9sil<\/p>\n\n\n\n

\n
Lire le rapport complet<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Summary Introduction and aim Hepatitis C is a key challenge to public health in Brazil. The objective of this paper was to describe the Brazilian strategy for hepatitis C to meet the 2030 elimination goal proposed by World Health Organization (WHO). Methods A mathematical modeling approach was used to estimate the current HCV-infected Brazilian population, and […]<\/p>\n","protected":false},"author":24,"featured_media":3105,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[9],"tags":[31,10,12],"publication-author":[760,754,756,753,755,758,764,757,765,752,763,494,653,761,762,759],"class_list":["post-2414","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication","tag-elimination","tag-hcv","tag-modelling","publication-author-almeida-ec","publication-author-benzaken-as","publication-author-catapan-e","publication-author-fernandes-n","publication-author-ferraz-ml","publication-author-ferreira-pra","publication-author-girade-r","publication-author-martinelli-a","publication-author-mendes-correa-mc","publication-author-pereira-gfm","publication-author-pessoa-mg","publication-author-razavi-h","publication-author-schmelzer-j","publication-author-souto-fjd","publication-author-vivaldini-s","publication-author-walsh-n"],"acf":[],"_links":{"self":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2414","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/comments?post=2414"}],"version-history":[{"count":11,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2414\/revisions"}],"predecessor-version":[{"id":7488,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/posts\/2414\/revisions\/7488"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media\/3105"}],"wp:attachment":[{"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/media?parent=2414"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/categories?post=2414"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/tags?post=2414"},{"taxonomy":"publication-author","embeddable":true,"href":"https:\/\/cdafound.org\/fr\/wp-json\/wp\/v2\/publication-author?post=2414"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}